12.When there is marked cellular injury, there is cell death. This microscopic appearance of myocardium is a mess because so many cells have died that the tissue is not recognizable. Many nuclei have become pyknotic (shrunken and dark) and have then undergone karorrhexis (fragmentation) and karyolysis (dissolution). The cytoplasm and cell borders are not recognizable.

12.有显著的细胞损伤，就有细胞坏死。太多的心肌细胞死亡导致镜下心肌细胞外观紊乱，组织结构不能辨认。细胞核固缩（缩小和深染），接着核碎裂（形成碎片）和核溶解（溶解消失）。细胞质和细胞边界不能辨认。