Peptic ulceration occurs in the stomach and duodenum. Both acute and chronic forms are founded, the latter being more common.
消化性溃疡包括胃溃疡和十二指肠溃疡。分为急性、慢性两种，并以后者较为常见。
Clinical Features. Approximately 10 per cent of the adult male population are affected by peptic ulceration. The male incidence is higher, the proportion being 3:2 for gastric ulcer and 10:1 for duodenal ulcer. Duodenal ulcers are three to four times as common as gastric ulcers and most occur between the ages of 30 and 40 years, a decade or so earlier than gastric ulcers. In about 20 per cent of the latter a duodenal ulcer is or has been present ant in almost all instances it precedes the gastric lesion.
消化性溃疡有如下临床特点：成年男性中大约有百分之十患有消化性溃疡病，男性发病率高些，男女发病率的比率是，胃溃疡3：2；十二指肠溃疡10：1。十二指肠溃疡发病率为胃溃疡发病率的三至四倍，而且大多数十二指肠的溃疡的患者，都是在三十至四十岁之间，比胃溃疡病人发病早十年左右。大约百分之二十的胃溃疡患者被发现患有或已经患有十二指肠溃疡，而且几乎所有这些病例均表明：十二指肠溃疡常常发生于胃溃疡之前。
The history is very important and the diagnosis may often be made on to alone. Periodic epigastria pain occurs after meals, discomfort from a gastric ulcer being noted half to one hour after food whilst the stomach is still full, gradually passing off as the organ empties, or relieved by vomiting. In a duodenal ulcer, a long post parricidal interval of two to three hours offend exists before pain is apparent and it may then occur immediately before next meal.Both food and alkalis relieve the pain initally,although relief is greater in a duodenal than in agastric ulcer. Involvement of the pancreas may produce backache which can mistakenly be attributed to an orthopedic lesion. Nocturnal pain, at times sufficient to wake the patient from sleep, is often a feature of a duodenal ulcer. Flatulent dyspepsia may be the main symptom and aggravation by a fatty diet will stimulate gall bladder disease. The appetite generally remains with loss of weight. Lassitude and malaise may occur with secondary anemia from chronic blood loss. Mental irritability is often prominent, but between attacks the patient is usually eel and symptom free. Remissions, initially lasting months or years, become shooter and the attacks more frequent. The latter may persist for days or weeks and are often related to dietary indiscretion or periods of intense worry or strain.
对于消化性溃疡患者，病史也很重要，而且往往仅依据病史，即可作出诊断，胃溃疡患者常在饭后出现上腹周期性疼痛，这是因为当食物仍在胃里时，由于胃溃疡而产生不适感觉，不适感随胃排空而慢慢消失或因呕吐而减轻。十二指肠溃疡患者的疼痛症状，则往往经过餐后两到三小时的较长间歇期，才于下餐饭前出现发作。在发病的最初阶段，由于食物和碱性物质的作用，患者的疼痛症状可得到减轻，而且十二指肠溃疡比胃溃疡的减痛效果更好。当病变累及胰脏时，则会产生背痛，这可能被误认为矫形损伤所致，夜间疼痛有时足以使病人从睡眠中痛醒——这也是十二指肠溃疡的一种常见的临床症状。肠胃消化不良也是溃疡病的主要症状，进食脂肪性食物能引起恶化这一点颇类似胆囊病。患者食欲一般较好，但由于惧怕疼痛有碍进食足量的食物，而造成体重减轻，由于慢性出血而造成的继发性出血，会引起疲倦和不适，患者常有明显的心情急躁易怒。但在两次发作之间，病人情况通常很好，也无明显的临床症状。起初，两次发作之间的缓解期可持续数月/数年，逐渐地缓解期越来越短，疾病发作越来越频繁，发作可持续数日或数周。溃疡病的发作常与饮食不慎、长期过分忧虑或情绪紧张有关。
On examination the main physical sign is tenderness in the epigastrium or right hypochondria, but between attacks this may be absent.
检查时，患者主要的体征为；上腹部和右季肋部有压痛，但在缓解期可无上述体征表现。
